homehealthcare NewsWhat is the link between Avascular Necrosis and COVID 19? Check here

What is the link between Avascular Necrosis and COVID-19? Check here

After black fungus or mucormycosis made matters worse for patients who recovered from COVID-19, now three survivors in Mumbai have been detected with avascular necrosis (AVN), or death of bone tissues. The patients, all aged below 40, are undergoing treatment in Mumbai’s PD Hinduja Hospital. They developed AVN two months after they suffered COVID-19.

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By CNBC-TV18 Jul 5, 2021 5:12:13 PM IST (Published)

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What is the link between Avascular Necrosis and COVID-19? Check here

After black fungus or mucormycosis made matters worse for patients who recovered from COVID-19, now three survivors in Mumbai have been detected with avascular necrosis (AVN), or death of bone tissues. The patients, all aged below 40, are undergoing treatment in Mumbai’s PD Hinduja Hospital. They developed AVN two months after they suffered COVID-19.

Doctors say both AVN and mucormycosis are associated with the usage of steroids during the COVID treatment.


What is AVN?

Avascular Necrosis, also called osteonecrosis, is the death of bone tissue when blood supply doesn’t reach the hip joint.

It can lead to tiny breakages in the bone and its eventual collapse. Besides, the bone can lose its smooth shape, potentially leading to severe arthritis.

Avascular Necrosis is common in people between 30 and 50 years of age.

Symptoms

Many people have no symptoms in the early stages, but pain and stiffness in joints shouldn’t be taken lightly. The pain can be mild or severe and usually develops gradually. If there is a pain in groin, thigh or buttock, it could be a symptom of avascular necrosis of the hip. Besides the hip, shoulder, knee, hand and foot can also be affected.

Those with the condition may also experience difficulty in climbing stairs or limp while walking.

Some people develop avascular necrosis on both sides of their bodies.

Causes

It is to be noted that in around 25 percent of AVN patients, the cause of interrupted blood flow is unknown, but it could be caused due to any of the following:

  • Steroid use: The use of high-dose corticosteroids, such as prednisone, is a common cause of avascular necrosis.
  • Bone or joint trauma: Dislocated joint due to any injury might damage nearby blood vessels. Cancer treatments with radiation can also weaken the bone and harm blood vessels.
  • Fat deposits on blood vessels: Fat (lipids) can block small blood vessels, reducing the blood flow to bones.
  • Medical conditions: Certain diseases such as sickle cell anemia, pancreatitis, diabetes, HIV/AIDS, systemic lupus erythematosus and Gaucher's disease can hamper the blood flow to the bone.
    • Excessive intake of alcohol: Consuming excessive alcohol every day for years leads to fat deposits in blood vessels.
    • Use of bisphosphonate: Long-term use of bisphosphonate, a medication to increase bone density, might contribute to developing AVN of the jaw.
    • Prevention

      Maintaining one’s general health is the best prevention for any disease, but here are some measures that can be followed:

      • Limit alcohol intake: As mentioned above excessive intake of liquor causes interruption in blood supply to bones, the best prevention is to stop heavy drinking.
      • Keep low cholesterol levels: As fat deposits in blood vessels can limit the supply of blood to bones, maintain cholesterol levels.
      • Don't smoke: Smoking also increases the risk.
      • How AVN is diagnosed?

        The disease is diagnosed through a physical examination of joint areas by a doctor, followed by imaging tests, which pinpoint the source of pain. Imaging test options include X-ray, MRI and CT scan, and bone scan.

        Treatment

        The goal is to prevent further bone loss. In the early stages of avascular necrosis, symptoms might be eased with medication and therapy like electrical stimulation where currents might encourage your body to grow new bone in place of the damaged one.

        If the avascular necrosis is fairly advanced, the doctor might recommend surgery.

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